Barcelona are unbeaten in nine meetings with Real Betis, winning six of them. Los Verdiblancos have also failed to win any of their last 15 home games against Barça, dating back to a Copa del Rey tie in 2011.
Real Betis vs Barcelona preview
Can Barcelona continue their excellent form? On Tuesday night, despite falling behind early, Hansi's Flick's side roared back to beat fellow title challengers Atlético Madrid 3-1 at Camp Nou. Raphinha rounded the goalkeeper to equalise, before Robert Lewandowski skied a penalty miles over the crossbar, one of the worst spot-kick you're ever likely to see. Nevertheless, second half goals from Dani Olmo and then Ferran Torres were enough to secure a crucial victory in Catalonia.

That made it five successive La Liga victories for the champions, maintaining their position at the top of the table, one point above Real Madrid, winning every league game since defeat in October's Clásico at the Bernabéu. This though will certainly be one of Barça's tougher assignments, so will they leave Estadio de La Cartuja with three more precious points on Saturday?
As for Real Betis, they have finished between fifth and seventh in each of the last five seasons, so are desperate to qualify for the Champions League for the first time since 2005. Well, Manuel Pellegrini's team will certainly come into this marquee fixture on a high, following victory in last Sunday's Gran Derbi. Second half goals from Pablo Fornals and then Sergi Altimira saw los Verdiblancos beat fierce rivals Sevilla 2-0 at Estadio Ramón Sánchez-Pizjuán, a match that had a 15 minute interruption towards the end, play suspended after home fans threw water bottles at Betis players.

Nevertheless, a memorable victory for Béticos everywhere, especially given that their side have only been beaten by Atlético Madrid since August, leaving them fifth in the table. Pellegrini heavily rotated for Wednesday's 4-1 Copa del Rey victory over fourth-tier Torrent, so his player will be raring to go at their temporary home the Cartuja, but can Betis defeat the league-leaders on Saturday?
Real Betis vs Barcelona head-to-head record
- Matches Played: 142.
- Real Betis Wins: 30. Draws: 26. Barcelona Wins: 86.
Real Betis team news
Manuel Pellegrini could name an unchanged lineup compared to the team that were victorious against Sevilla in last Sunday's derby.

Antony remains suspended, having been sent off for kicking Joel Roca of Girona in the head a fortnight ago, while Isco is sidelined, after being on the wrong end of a dangerous tackle by Sofyan Amrabat, his own teammate, during a recent Europa League victory over Utrecht.
Real Betis predicted lineup vs Barcelona: (4-3-3): Valles; Ruibal, Natan, Bartra, Gómez; Deossa, Roca, Fornals; García, Abde, Hernández.
Real Betis player to watch vs Barcelona
In the absence of Antony and Isco, Abde Ezzalzouli will be Betis' primary attacking threat. He joined Barcelona as a teenager, but made only 14 appearances for the first-team, but can Abde now add to his six goals so far this season?
Barcelona team news
As for Hansi Flick, he is without midfield trio Frenkie de Jong, Fermín López and Gavi, while defender Ronald Araújo has been given some time away from football, following his red card at Chelsea.

Further forward, Raphinha scored his first goal since 14 September on Tuesday, largely due to a hamstring injury, but his return means Ferran Torres and Marcus Rashford are both likely to once again begin the evening on the bench.
Barcelona predicted lineup vs Real Betis: (4-3-3): García; Koundé, Cubarsí, Martín, Balde; Eric García, Pedri, Dani Olmo; Lamine Yamal, Torres, Lewandowski.
Barcelona player to watch vs Real Betis
Lamine Yamal has seven goals to his name this season, while the teenager scored against Betis during a 5-1 demolition in last season's Copa del Rey, so can he repeat that feat in Seville?
Real Betis vs Barcelona prediction
Without their two star attackers, we do not believe Betis will be able to upset the odds in this one, backing Barcelona to be simply too strong at Estadio de La Cartuja on Saturday night, although goals are guaranteed, as is always the case with Hansi Flick's Barça team: Real Betis 1-3 Barcelona.
Real Betis vs Barcelona FAQs - La Liga
How to watch Real Betis vs Barcelona in La Liga on TV channel?
Real Betis vs Barcelona in La Liga will be available on the following TV channels;
- UK: Premier Sports Player.
- USA: ESPN Select.
- Canada: TSN+
How to watch Real Betis vs Barcelona in La Liga on live streaming?
Real Betis vs Barcelona in La Liga will be available on the following streaming services;
- UK: Premier Sports Player.
- USA: ESPN Select.
- Canada: TSN+
What is the date and kick-off time for Real Betis vs Barcelona in La Liga?
Real Betis vs Barcelona takes place on Saturday 6 December 2025, with kick off at 17:30 (GMT), 12:30 (ET) & 9:30 (PT).
