These two clubs have amazingly only ever met once before. This came in the first round of the UEFA Cup in 1972/73, when goals from Kevin Keegan and then Emlyn Hughes saw Liverpool win 2-0 at Anfield, before drawing 0-0 in Germany, en route to winning the competition for the first time, beating Borussia Mönchengladbach in the final.
More recently, Frankfurt have won only one of six home matches against English opposition in the 21st century. Liverpool are unbeaten in 14 meetings with Bundesliga sides, dating back to 2002, winning each of the last five.
Frankfurt vs Liverpool preview
When does a blip become a crisis? Well, on Sunday, in one of the biggest shocks in modern Premier League history, Liverpool were beaten 2-1 by fierce rivals Manchester United at Anfield. After falling behind bang on 60 seconds, Cody Gakpo equalised late on, seemingly setting up a grand-stand finish, only for Harry Maguire's towering header to pinch the points for Man United shortly after.
This is a fourth successive defeat for Arne Slot's team, following a trio of away loses in a week before the international break, beaten by Crystal Palace, Galatasaray and then Chelsea. This is the first time since November 2014 that the Reds have lost four on the spin; they have not suffered five successive defeats since September 1953, finishing rock bottom of the First Division back then.
In the Champions League, Virgil van Dijk's towering stoppage time header saw them beat Atlético Madrid 3-2 on Merseyside on matchday one, followed by that aforementioned defeat in İstanbul. After this, Liverpool will welcome Real Madrid, PSV Eindhoven and Qarabağ to Anfield, while also traveling to Inter Milan and Marseille, which certainly is not an easy set of fixtures, making it vital that they leave Waldstadion with something, simply to boost morale and confidence of nothing else.
Eintracht Frankfurt meantime continue to be Europe's great entertainers; their ten outings this season have produced 54 goals, meaning one is scored every 17 minutes on average. Die Adler's two Champions League games very much offer a microcosm, smashing Galatasaray 5-1 in their opener, before themselves being demolished 5-1 by Atlético Madrid at the Metropolitano 12 nights later.
Meantime, in the Bundesliga, Dino Toppmöller's team sit seventh, having won three and lost three to date, drawing 2-2 with Freiburg on Sunday; Jonathan Burkardt scoring a brace at Europa-Park Stadion. Beforehand, Frankfurt were demolished 3-0 by Bayern Munich before the international break, a goal down inside 14 seconds, underlining their limitations. Nevertheless, die Adler will fancy their chances of adding to struggling Liverpool's misery at Waldstadion on Wednesday night.
Eintracht Frankfurt vs Liverpool head-to-head record
- Matches Played: 2.
- Eintracht Frankfurt Wins: Zero. Draws: 1. Liverpool Wins: 1.
Frankfurt team news
Despite their eratic and chaotic scorelines, Dino Toppmöller's team is largely very settled.
Ritsu Dōan is a dangerous attacker, having scored four times this season, while 19 year old Can Uzun is certainly an exciting talent to keep an eye out for.
Eintracht Frankfurt predicted lineup vs Liverpool: (5-2-2-1): Kauã Santos; Kristensen, Koch, Theate, Amenda, Brown; Larsson, Chaïbi, Uzun, Dōan; Burkardt.
Frankfurt player to watch vs Liverpool
Jonathan Burkardt's brace against Freiburg on Sunday took his tally to seven for the season, three of which have come in the Champions League, so can he add to his tally?
Liverpool team news
Alisson remains sidelined due to a hamstring injury, so Giorgi Mamardashvili will continue to deputise.
Both Florian Wirtz and Hugo Ekitiké were left on the bench while both Mohamed Salah and Alexander Isak, so it'll be interesting to see who Arne Slot goes for in attack. Lastly, Conor Bradley is one yellow card away from being suspended in this competition.
Liverpool predicted lineup vs Eintracht Frankfurt: (4-3-3): Mamardashvili; Bradley, Konaté, van Dijk, Robertson; Gravenberch, Mac Allister, Szoboszlai; Salah, Ekitiké, Gakpo.
Liverpool player to watch vs Frankfurt
Cody Gakpo has scored in back-to-back games against Chelsea and Manchester United, so will he be Liverpool's most-dangerous attacker again?
Frankfurt vs Liverpool prediction
This clash guarantees goals, but we are not backing Liverpool to get back to winning ways at Waldstadion, albeit they will stop the rot in terms of defeats: Eintracht Frankfurt 2-2 Liverpool.
Frankfurt vs Liverpool FAQs - UEFA Champions League
How to watch Eintracht Frankfurt vs Liverpool in the Champions League on TV channel?
Eintracht Frankfurt vs Liverpool in the Champions League will be available on the following TV channels;
- UK: TNT Sports 1.
- USA: TUDN USA, Univision NOW & Paramount+
- Canada: DAZN Canada
How to watch Eintracht Frankfurt vs Liverpool in the Champions League on live streaming?
Eintracht Frankfurt vs Liverpool in the Champions League will be available on the following streaming services;
- UK: Discovery+
- USA: TUDN.com, UniMás & Paramount+
- Canada: DAZN Canada
What is the date and kick-off time for Eintracht Frankfurt vs Liverpool in the Champions League?
Eintracht Frankfurt vs Liverpool takes place on Wednesday 22 October 2025, with kick off at 20:00 (BST), 15:00 (EDT) & 12:00 (PDT).