Manchester United are winless in ten visits to Anfield, dating back to 2016, albeit five of these trips have yielded draws, including both of the last two.
Liverpool vs Manchester United preview
These two clubs, located a mere 31 miles apart, have won 40 top-flight English titles between them, as well as a total of 137 major honours all told, but both badly need a win in Sunday's blockbuster.
Premier League champions Liverpool began this campaign with seven straight victories across all competitions, but now come into this fixture following three straight defeats. In both of their last two league games, Arne Slot's side have been beaten 2-1 in London, conceding stoppage time goals on both occasions, first beaten by Crystal Palace before suffering a similar sucker-punch against Chelsea at Stamford Bridge a fortnight ago.
In between, the Reds also lost 1-0 in İstanbul against Galatasaray in the Champions League, which is likely to prove pretty inconsequential, but exacerbates the ongoing malaise. This is the start of another crucial week for Liverpool, who travel to Eintracht Frankfurt on Wednesday, before a tricky trip to Brentford next Saturday night. Ahead of this one, they are seeking to avoid losing four successive matches for the first time since November 2014 under Brendan Rodgers, so could a visit from their fiercest rivals be the catalyst the champions need to reignite the touch paper?
As for Manchester United, they may begin the weekend tenth, five points below their hosts, but perhaps travel to Merseyside with a sense of belief. Before the international break, Rúben Amorim's team secure a third successive win at Old Trafford. Following chaotic victories over Burnley and Chelsea, goals from Mason Mount and Benjamin Šeško were enough to defeat Sunderland.
On the road however, the Red Devils are yet to claim a victory so far, drawing at Fulham before back-to-back defeats at Manchester City and Brentford, shipping three goals both times. Between this international break and the next, Man United will also face Brighton, Nottingham Forest and Spurs, which is a tricky four-match stretch, one that'll really gauge the progress Amorim's team have made. So, can they add to Liverpool's misery, or will the Red Devils' latest false dawn prove to be just that?
Liverpool vs Manchester United head-to-head record
- Matches Played: 244.
- Liverpool Wins: 82. Draws: 71. Manchester United Wins: 91.
Liverpool team news
Goalkeeper Alisson suffered a hamstring injury against Galatasaray, so there will be a home Premier League debut for Giorgi Mamardashvili, a more than capable understudy.
Out-field, Ibrahima Konaté did not play a single minute for France, while Ryan Gravenberch was hooked at half time against Finland last Sunday, but both should be fit to feature in this one.
Right-back continues to be a conundrum for Arne Slot, with Conor Bradley hooked at half time at Stamford Bridge, Dominik Szoboszlai subsequently moving back into that position, while Jeremie Frimpong is already seemingly not trusted to occupy that spot.
Lastly, in attack, neither Florian Wirtz nor Hugo Ekitiké started at Chelsea, so will either, or both, return with Alexnader Isak still searching for his first Premier League goal in red?
Liverpool predicted lineup vs Manchester United: (4-3-3): Mamardashvili; Szoboszlai, Konaté, van Dijk, Kerkez; Gravenberch, Mac Allister, Wirtz; Salah, Ekitiké, Gakpo.
Liverpool player to watch vs Manchester United
Mohamed Salah scored twice for Egypt against Djibouti in Casablanca last week, thereby helping the Pharaohs qualify for only their fourth World Cup. Salah has scored 16 career goals against Man United, of which six have come at Anfield, so will he bag just his fourth goal of the campaign?
Manchester United team news
Senne Lammens made his Manchester United debut against Sunderland, keeping a clean sheet, and supporters were clearly impressed, singing "are you Schmeichel in disguise", a ringing endorsement. Thus, the young Belgian will continue to don the gloves, chosen over the error-prone Altay Bayındır.
Meantime, Lisandro Martínez and Noussair Mazraoui remain sidelined, while Leny Yoro could keep his place over Harry Maguire as part of the back three, with Patrick Dorgu returning at wing-back.
Rúben Amorim has favoured deploying Bruno Fernandes in his midfield two in recent weeks, which would certainly be bold at Anfield, but perhaps the presences of Mason Mount, scorer against Sunderland of course, helps alleviate that, likely to be chosen over fit again Matheus Cunha.
Manchester United predicted lineup vs Liverpool: (3-4-2-1): Lammens; Yoro, de Ligt, Shaw; Dalot, Casemiro, Fernandes, Dorgu; Mbeumo, Mount, Šeško.
Manchester United player to watch vs Liverpool
Benjamin Šeško has scored during Manchester United's last two matches against Brentford and Sunderland, so can the Slovenian continue this hot streak and make himself a hero?
Liverpool vs Manchester United prediction
Despite their recent poor form, we can't see beyond a resounding Liverpool win, perhaps not the 7-0 they enjoyed in March 2023, but a scoreline equally as one-sided: Liverpool 3-0 Manchester United.
Liverpool vs Manchester United FAQs - Premier League
How to watch Liverpool vs Manchester United in the Premier League on TV channel?
Liverpool vs Manchester United in the Premier League will be available on the following TV channels;
- UK: Sky Sports Main Event, Premier League & Ultra HD.
- USA: fuboTV, NBC, Telemundo & Deportes En Vivo
- Canada: Fubo Sports Network Canada
How to watch Liverpool vs Manchester United in the Premier League on live streaming?
Liverpool vs Manchester United in the Premier League will be available on the following streaming services;
- UK: SkyGo & NOW TV.
- USA: fuboTV, nbcsports.com, USA Network & Telemundo
- Canada: fuboTV Canada
What is the date and kick-off time for Liverpool vs Manchester United in the Premier League?
Liverpool vs Manchester United takes place on Sunday 19 October 2025, with kick off at 16:30 (BST), 11:30 (EDT) & 8:30 (PDT).