Liverpool have won all three previous home games against PSV, never losing any of their nine home matches against Dutch clubs, winning eight of them.
PSV meantime are winless in seven visits to England, dating back to a 1-0 victory over Tottenham in 2008, albeit they did beat a heavily-rotated Liverpool 3-2 in last season's league phase at home.
Liverpool vs PSV Eindhoven preview
Liverpool have officially entered a crisis, so can they claim a much-needed morale-boosting victory? On Saturday, Arne Slot's side were beaten again, this time demolished 3-0 by Nottingham Forest in a truly shambolic display at Anfield. Having been battered by the scoreline at Manchester City before the international break, this is the first time since April 1965 that the Reds have lost back-to-back league matches by a three goal margin. Overall though, the reigning champions have suffered defeat in six of their last seven league fixtures, slipping all the way down to 11th in the table.
Meantime, in the Champions League, Liverpool were supposed to be back after beating Real Madrid 1-0 at Anfield earlier this month; Alexis Mac Allister's header the only goal in a dominant victory. This means Slot's side have won three out of four in this competitions, also enjoying wins over Atlético Madrid and Eintracht Frankfurt, defeated by Galatasaray in İstanbul. Their next two Champions League games will see them visit Inter Milan and then Olympique Marseille, which certainly won't be easy, so the Reds are under pressure to pick up all three points in this one.
As for PSV Eindhoven, considering their hosts trials and tribulations, they'll surely fancy their chances of a famous upset. Peter Bosz's team have collected five points in the league phase so far, most notably demolishing Napoli 6-2 at the Philips Stadion last month; Dennis Man at the double. That aside, the Red and Whites have suffered a shock home defeat at the hands of Royale Union Saint-Gilloise and held both Bayer Leverkusen and Olympiacos to 1-1 draws on the road, with Ricardo Pepi's 93rd minute equaliser pinching a point in Piraeus three weeks ago.
With Atlético Madrid, Newcastle and Bayern Munich their three remaining opponents, PSV still have plenty of work to do if they're to reach the knockout stages. Domestically, chasing a third successive Eredivisie title, something they've not achieved since 2008, Bosz's side are six points clear at the top of the table. Saturday's 1-0 victory over NAC Breda, Guus Til the only scorer, made it seven straight league wins, so they'll more than arrive on Merseyside full of confidence. So, will Liverpool get back to winning ways, or can PSV pile on the misery?
Liverpool vs PSV Eindhoven head-to-head record
- Matches Played: 7.
- Liverpool Wins: 5. Draws: 1. PSV Eindhoven Wins: 1.
Liverpool team news
Arne Slot is without Giovanni Leoni, Conor Bradley and Florian Wirtz, limiting his options.
In Bradley's absences on Saturday, Dominik Szoboszlai deputised at right-back, with Curtis Jones coming into midfield. Here, Joe Gomez is the alternative option in that position while, on the other side, Andy Robertson could return in place of Miloš Kerkez.
In a positive development, Alisson started against Nottingham Forest, his first appearance since sustaining a hamstring injury at the Ali Sami Yen on 30 September. Lastly, Alexander Isak led the line at the weekend, but touched the ball only 14 times before being replaced by Hugo Ekitiké in the 68th minute, so who will get the nod this time?
Liverpool predicted lineup vs PSV Eindhoven: (4-3-3): Alisson; Szoboszlai, Konaté, van Dijk, Robertson; Gravenberch, Mac Allister, Jones; Salah, Ekitiké, Gakpo.
Liverpool player to watch vs PSV Eindhoven
Mohamed Salah has scored 45 Champions League goals for Liverpool, netting against 25 different opponents in the competition, so can he add PSV to that list?
PSV Eindhoven team news
Peter Bosz is without Alassane Pléa due to a long-term knee injury, so USMNT striker Ricardo Pepi is likely to lead the line, starting alongside his international teammate Sergiño Dest.
Elsewhere, goalkeeper Matěj Kovář has spent time at Swindon Town and Burton Albion before making his way to Eindhoven, while Jerdy Schouten is set to get the nod over Ryan Flamingo in defence.
PSV Eindhoven predicted lineup vs Liverpool: (4-2-3-1): Kovář; Dest, Schouten, Gasiorowski, Salah-Eddine; Mauro Júnior, Verrman, Man, Saibari, Perišić; Pepi.
PSV Eindhoven player to watch vs Liverpool
At 36 years old, Ivan Perišić is still a key figure in this PSV team, scoring one goal and registering eight assists already this season. He won at Anfield with Inter back in March 2022, albeit Liverpool progressed on aggregate, so can the veteran fire his new side to a famous win here?
Liverpool vs PSV Eindhoven prediction
Predicting any Liverpool match right now feels like a fool's errand. This game should guarantee goals, but who knows what to expect from Slot's team at the moment: Liverpool 2-1 PSV Eindhoven.
Liverpool vs PSV Eindhoven FAQs - UEFA Champions League
How to watch Liverpool vs PSV Eindhoven in the Champions League on TV channel?
Liverpool vs PSV Eindhoven in the Champions League will be available on the following TV channels;
- UK: TNT Sports 2.
- USA: Paramount+
- Canada: DAZN Canada
How to watch Liverpool vs PSV Eindhoven in the Champions League on live streaming?
Liverpool vs PSV Eindhoven in the Champions League will be available on the following streaming services;
- UK: Discovery+
- USA: Paramount+
- Canada: DAZN Canada
What is the date and kick-off time for Liverpool vs PSV Eindhoven in the Champions League?
Liverpool vs PSV Eindhoven takes place on Wednesday 26 November 2025, with kick off at 20:00 (GMT), 15:00 (ET) & 12:00 (PT).