Chelsea are winless in 12 visits to Old Trafford, dating back to May 2013, albeit seven of these encounters have produced draws.
Manchester United vs Chelsea preview
After suffering a couple of reality checks this week, can Chelsea claim a statement victory on Saturday evening? Last Saturday night, the Blues were denied victory at West London rivals Brentford, fighting back from a goal down to lead, Cole Palmer and Moisés Caicedo the scorers, only to concede a 94th minute equaliser, coming via a long throw. Then, on Wednesday night, Enzo Maresca's side were beaten for the first time this season, swatted aside 3-1 by Bayern Munich upon their Champions League return, second best throughout in Bavaria.
If they didn't know already, this crystallised the fact that the jump up in difficulty level from Conference League to Champions League is enormous. Domestically, Chelsea do remain unbeaten, albeit they've drawn two of four matches, and this'll be their first Premier League fixture of the campaign that isn't a London derby, so can the Blues win at Old Trafford for the first time in 12 years?
As for Manchester United, the last decade or so has been one long reality check, but they've surely hit a new nadir this season. Last Sunday, the Red Devils were demolished 3-0 by Manchester City in the derby at the Etihad, rarely threatening and beaten with ease. This defeat means Rúben Amorim has now taken just 31 points from 31 league games in charge, leaving Man United bottom of a table since his appointment, containing clubs who've been in the division both this season and last.
This EFL Cup exit at Grimsby was rock-bottom, or at least they'll hope, and the Red Devils have still won only once all season, beating Burnley 3-2 thanks to Bruno Fernandes' injury time penalty. So, can Amorim's team claim a much-needed statement win, or will they slump to yet another defeat?
Manchester United vs Chelsea head-to-head record
- Matches Played: 197.
- Manchester United Wins: 83. Draws: 57. Chelsea Wins: 57.
Manchester United team news
Unlike their visitors, Manchester United have a full week to prepare for this fixture, something they should get used to, given that they're not in Europe as well as their early League Cup elimination.
In goal, there is likely to be a debut for deadline day signing Senne Lammens, after Altay Bayındır surprisingly kept his place for the Manchester derby. Meantime, Diogo Dalot, Mason Mount and Matheus Cunha are sidelined, but Lisandro Martínez could be back on the bench, hoping to feature for the first time since 2 February due to an anterior cruciate ligament injury suffered against Palace.
Manchester United predicted lineup vs Chelsea: (3-4-2-1): Lammens; Yoro, de Ligt, Shaw; Mazraoui, Ugarte, Fernandes, Dorgu; Mbeumo, Amad, Šeško.
Manchester United player to watch vs Chelsea
Bryan Mbeumo has scored three times across his last four meetings with Chelsea, all coming at Stamford Bridge, so having been on target during Man United's last match at Old Trafford, could he be the hero come Saturday evening?
Chelsea team news
Enzo Maresca, in contrast, will surely have to rotate, following an energy-sapping trip to Munich; Levi Colwill, Benoît Badiashile, Roméo Lavia, Dário Essugo and Liam Delap are all sidelined.
Against Bayern on Wednesday, Maresca deployed Reece James in midfield, a ploy that worked so well against PSG in the Club World Cup Final, but is the club captain capable of starting once again?
Jorrel Hato, Wesley Fofana, Facundo Buonanotte and Jamie Gittens were all surprise starters at Brentford a week ago, but how much will Maresca rotate at Old Trafford?
Chelsea predicted lineup vs Manchester United: (4-3-3): Sánchez; Gusto, Adarabioyo, Chalobah, Cucurella; Caicedo, Fernández, Palmer, Estêvão, Neto; João Pedro.
Chelsea player to watch vs Manchester United
Alejandro Garnacho will quickly come up against his former club here, having come off the bench during Chelsea's last two matches. The Argentine international scored 26 goals in 144 appearances for Manchester United, so can he net against them as he returns to Old Trafford?
Manchester United vs Chelsea prediction
We are backing Chelsea to claim that illusive first victory at Old Trafford since 2013, able to utilise their squad depth while, frankly, Man United are a complete mess: Manchester United 1-3 Chelsea.
Manchester United vs Chelsea FAQs - Premier League
How to watch Manchester United vs Chelsea in the Premier League on TV channel?
Manchester United vs Chelsea in the Premier League will be available on the following TV channels;
- UK: Sky Sports Main Event, Premier League & Ultra HD.
- USA: fuboTV, NBC, Telemundo & Deportes En Vivo
- Canada: Fubo Sports Network Canada
How to watch Manchester United vs Chelsea in the Premier League on live streaming?
Manchester United vs Chelsea in the Premier League will be available on the following streaming services;
- UK: SkyGo & NOW TV.
- USA: fuboTV, nbcsports.com, USA Network & Telemundo
- Canada: fuboTV Canada
What is the date and kick-off time for Manchester United vs Chelsea in the Premier League?
Manchester United vs Chelsea takes place on Saturday 20 September 2025, with kick off at 17:30 (BST), 12:30 (EDT) & 9:30 (PDT).