These two clubs have only ever met once before, doing so in the UEFA Cup semi-finals in 2004, drawing 0-0 on Tyneside before Didier Drogba's brace at Stade Vélodrome saw OM prevail 2-0.
Overall, Olympique de Marseille are winless in 12 meetings with English clubs, dating back to 2010, while Newcastle have won just one of seven trips to France, beating Sochaux 21 years ago.
Marseille vs Newcastle preview
Can Newcastle claim a fourth successive Champions League victory? Since losing to Barcelona on the opening night of this competition, they have won all three matches, scoring nine goals and conceding none. The Magpies demolished Royale Union Saint-Gilloise 4-0 in Brussels before back-to-back home victories over Benfica and Athletic Club, with Dan Burn and Joelinton the scorers in the latter. This leaves the Toon Army flying high in sixth place, albeit with trips to Bayer Leverkusen and PSG as well as a home game against PSV their remaining fixtures, which certainly will not be easy.
Meantime, in the Premier League, Howe's side claimed a much-needed, massive victory on Saturday evening. Harvey Barnes was the hero, scoring twice in seven minutes as Newcastle beat Manchester City 2-1 at a rocking St James' Park. On the road however, the Magpies have lost each of their last three in the Premier League, their sole success in seven attempts in any competition that aforementioned victory at Stade Constant Vanden Stock over USG. So, the members of the Toon Army traveling to Southern France may be doing so more in hope than expectation.
As for Olympique de Marseille, they have not won Ligue 1 since 2010 nor reached the Champions League knockout phase since 2012, but are generally flying right now. On Friday night, les Phocéens demolished Nice 5-1 in the French Riviera, with Mason Greenwood bagging a brace, while Pierre-Emerick Aubameyang, Tim Weah and Igor Paixão were also on target. This makes it three league wins in a row, and eight victories from their last ten, meaning les Olympiens are second in Ligue 1, just two points below serial champions and hated rivals Paris Saint-Germain.
Meantime, in the Champions League, Roberto De Zerbi's team are in desperate need of some points. Marseille have lost three of their four league phase fixtures thus far, narrowly beaten by Real Madrid at the Bernabéu and Sporting in Lisbon, before a controversial 1-0 defeat at home to Atalanta, the only goal coming in stoppage time. OM did demolish Ajax 4-0 at home in September, Paixão at the double that night, and their remaining opponents are Union Saint-Gilloise, Liverpool and Club Brugge, so they are very much still in the hunt to progress. Come Tuesday evening, Stade Vélodrome will be absolutely rocking, so can Marseille add to Newcastle's away day misery?
Olympique Marseille vs Newcastle United head-to-head record
- Matches Played: 2.
- Olympique Marseille Wins: 1. Draws: 1. Newcastle United Wins: Zero.
Marseille team news
Roberto De Zerbi is without Nayef Aguerd, Amir Murillo, Hamed Traorè and Amine Gouiri due to injury, but does have plenty of talent from which to choose.
USMNT international Tim Weah could be continued to be deployed at right-back, with Pierre-Emile Højbjerg and England international Angel Gomes the first-choice midfield pairing. Igor Paixão's goal in Nice on Friday was his fifth of the campaign so far.
Olympique Marseille predicted lineup vs Newcastle United: (4-3-3): Rulli; Weah, Pavard, Balerdi, Emerson; Gomes, Højbjerg, Vermeeren; Greenwood, Paixão, Aubameyang.
Marseille player to watch vs Newcastle
36 year old Pierre-Emerick Aubameyang is OM's main man for goals, netting six so far this season, while he has bagged six in his last six against Newcastle.
Newcastle team news
Dan Burn can return, having been suspended against Manchester City at the weekend, likely to displace Lewis Hall at left-back, while Anthony Gordon and Yoane Wissa remain sidelined.
On the opposite side, Tino Livramento came in for Kieran Trippier, while Jacob Murphy and weekend hero Harvey Barnes will keep their places over Anthony Elanga out-wide.
Newcastle United predicted lineup vs Olympique Marseille: (4-3-3): Pope; Livramento, Thiaw, Botman, Burn; Tonali, Guimarães, Joelinton; Murphy, Woltemade, Barnes.
Newcastle player to watch vs Marseille
Nick Woltemade has been excellent since arriving from Stuttgart, scoring six times, including netting at Royale Union Saint-Gilloise during their only Champions League away games thus far.
Marseille vs Newcastle prediction
This game is not one to be missed, with goals certainly guaranteed, but we are backing Marseille to make home advantage count at Stade Vélodrome: Olympique Marseille 2-1 Newcastle United.
Marseille vs Newcastle FAQs - UEFA Champions League
How to watch Marseille vs Newcastle in the Champions League on TV channel?
Olympique Marseille vs Newcastle United in the Champions League will be available on the following TV channels;
- UK: TNT Sports 2.
- USA: CBS Sports Network & Paramount+
- Canada: DAZN Canada
How to watch Marseille vs Newcastle in the Champions League on live streaming?
Olympique Marseille vs Newcastle United in the Champions League will be available on the following streaming services;
- UK: Discovery+
- USA: Paramount+
- Canada: DAZN Canada
What is the date and kick-off time for Marseille vs Newcastle in the Champions League?
Olympique Marseille vs Newcastle United takes place on Tuesday 25 November 2025, with kick off at 20:00 (GMT), 15:00 (ET) & 12:00 (PT).