Arsenal have never lost to Czech opposition, winning eight of their ten previous encounters.
Slavia Prague have won just one of their last 13 clashes with English clubs, their most-recent such home win coming against Leeds at the old Stadion Evžena Rošického in the UEFA Cup in March 2000.
Slavia Prague vs Arsenal preview
Can Arsenal continue their winning streak? On Saturday, the Gunners swatted aside Burnley 2-0 at Turf Moor, thanks to first half headers from Viktor Gyökeres and then Declan Rice. This makes it five successive victories in the Premier League, the first time Mikel Arteta's team have achieved that since May 2024, leaving them clear at the top of the table. Across all competitions, Arsenal have now won seven in a row, keeping a clean sheet in all of these matches, on the cusp of equalling the club record of eight successive shutouts, set in 1903.

In Champions League terms meantime, the Gunners have played three, won three, scored eight goals and conceded zero. A fortnight ago, they crushed Atlético Madrid 4-0 in North London, all the goals coming during a 13 minute second half spree, in which Gabriel and Gabriel Martinelli were on target, before Gyökeres scored twice in three minutes. With Bayern Munich up next in this competition, will Arsenal maintain their perfect record in the league phase in the Czech capital?
As for Slavia Prague, they remain unbeaten in the Czech First League, following Saturday's 2-0 victory over Baník Ostrava, thereby joint top alongside fierce rivals Sparta. On the continent, the Slavists are featuring in the Champions League proper for the first time since 2019, with this only the club's third appearance in the competition's group stage overall.

Well, the Red and Whites are still searching for the first victory of the campaign, coming closest back on matchday one. Youssoupha Mbodji's brace had them 2-0 up when Bodø/Glimt visited Prague, only for the Norwegian champions to pinch a point in stoppage time. Since then, Jindřich Trpišovský's side have twice visited Northern Italy, demolished 3-0 by Inter at San Siro, before a backs to the wall goalless draw against Atalanta in Bergamo a fortnight ago. So, Slavia Prague will be no pushovers, but an Arsenal victory is certainly the most likely outcome at Fortuna Arena.
Slavia Prague vs Arsenal head-to-head record
- Matches Played: 4.
 
- team1 Wins: Zero. Draws: 2. Arsenal Wins: 2.
 
Slavia Prague team news
Jindřich Trpišovský is without Tomáš Holeš, Igoh Ogbu, captain Jan Bořil, Dominik Javorček and Ivan Schranz all due to injury.

Czech international Lukáš Provod will be donning the armband, looking to supporter compatriot Tomáš Chorý in attack.
Slavia Prague predicted lineup vs Arsenal: (3-4-1-2): Markovič; Zima, Chaloupek, Vlček; Moses, Dorley, Zafiris, Sanyang; Provod, Chorý, Chytil.
Slavia Prague player to watch vs Arsenal
Mojmír Chytil scored his fourth goal of the season at the weekend, yet to net in the Champions League, so can he change that and end Arsenal's clean sheet streak?
Arsenal team news
Martín Zubimendi is suspended, having been cautioned in all three Champions League games thus far, while Martin Ødegaard, Noni Madueke, Kai Havertz and Gabriel Jesus remain sidelined, with Gabriel Martinelli also a doubt.
Meantime, after scoring at Turf Moor, Viktor Gyökeres was replaced at half time on Saturday, which may have only been precautionary, but the Swede may well not be risked, with a trip to high-flying Sunderland to come on Saturday in mind.

At the back, Myles Lewis-Skelly is set to start a third successive Champions League match, while any of Piero Hincapié, Cristhian Mosquera or Benjamin White could be rotated in, especially considering both centre-backs Gabriel and William Saliba have suffered knocks in recent weeks. Lastly, Declan Rice would sit out the clash with Bayern Munich later this month if cautioned.
Arsenal predicted lineup vs Slavia Prague: (4-3-3): Raya; White, Mosquera, Gabriel, Lewis-Skelly; Nørgaard, Rice, Eze; Saka, Trossard, Merino.
Arsenal player to watch vs Slavia Prague
Bukayo Saka has 11 goals to his name in the Champions League, while he was on target when Arsenal last visited Prague in April 2021, a 4-0 Europa League win, so will he repeat the trick?
Slavia Prague vs Arsenal prediction
We are backing Arsenal to both win and keep a clean sheet at the Fortuna Arena because, well, that is what Mikel Arteta's team have been doing for some time now: Slavia Prague 0-2 Arsenal.
Slavia Prague vs Arsenal FAQs - UEFA Champions League
How to watch Slavia Prague vs Arsenal in the Champions League on TV channel?
Slavia Prague vs Arsenal in the Champions League will be available on the following TV channels;
- UK: TNT Sports 1.
 
- USA: Paramount+, Univision NOW & TUDN USA.
 
- Canada: DAZN Canada
 
How to watch Slavia Prague vs Arsenal in the Champions League on live streaming?
Slavia Prague vs Arsenal in the Champions League will be available on the following streaming services;
- UK: Discovery+
 
- USA: Paramount+, UniMás & TUDN.com.
 
- Canada: DAZN Canada
 
What is the date and kick-off time for Slavia Prague vs Arsenal in the Champions League?
Slavia Prague vs Arsenal takes place on Tuesday 4 November 2025, with kick off at 17:45 (GMT), 12:45 (ET) & 9:45 (PT).
