Inter had won four successive encounters with Roma for the first time since 1999 before the Giallorossi's 1-0 victory at San Siro in April that cost the Nerazzurri the Scudetto. Thus, Roma are seeking back-to-back wins over Inter for the first time in eight years.
Roma vs Inter Milan preview
Both have made bright starts to the new Serie A season, so who will underline their title credentials with a victory in the Eternal City on Saturday night? Of the two, it is Roma who kick off three points better off, having claimed five victories out of six so far. Before the international break, the Giallorossi fought back from a goal down to beat Fiorentina 2-1 at the Artemio Franchi, with Matías Soulé equalising before Bryan Cristante bagged, what turned out to be, the winner after half an hour.
Thus, Gian Piero Gasperini's side have collected 15 points to date, most notably beating fierce rivals Lazio 1-0 in last month's Derby della Capitale. Roma's sole defeat came against Torino in August, which leaves them second, currently boasting the best defence in Serie A, having only conceded two goals. The Giallorossi have not won the Scudetto since 2001, but Gasperini's appointment in the summer has raised expectation levels, albeit this will be their first massive test of the campaign.
As for Internazionale Milano, having won the title in 2024, they failed to retain the Scudetto on the final day of last season, but are very much among the front runners to reclaim the trophy. However, led by rookie manager Cristian Chivu, the Nerazzurri actually suffered back-to-back defeats earlier this season, beaten by Udinese at San Siro, before a thrilling 4-3 Derby d'Italia defeat at Juventus.
Since then though, Inter have responded with three straight Serie A victories, most recently swatting aside Cremonese 4-1 at home; Lautaro Martínez, Ange-Yoan Bonny, Federico Dimarco and Nicolò Barella the scorers. Il Biscione have also flexed their muscles in the Champions League, beating both Ajax 2-0 and then Slavia Prague 3-0. Next Saturday evening, last season's top two will go head-to-head when Napoli welcome Inter to the Stadio Diego Armando Maradona. Thus, this is the first of two crucial visits south for the Nerazzurri, so can they claim a statement victory in the capital?
Roma vs Inter Milan head-to-head record
- Matches Played: 218.
- Roma Wins: 63. Draws: 57. Inter Milan Wins: 98.
Roma team news
Gian Piero Gasperini is without the injured trio Angeliño, Edoardo Bove and Leon Bailey.
Roma will continue to operate out of Gasperini's classic 3-4-2-1, with Manu Koné key at the base of midfield. In attack, Artem Dovbyk led the line against Fiorentina but, having scored the only goal as Ireland beat Armenia on Tuesday, Evan Ferguson will be hoping to start this time.
Roma predicted lineup vs Inter Milan: (3-4-2-1): Svilar; Çelik, Mancini, Ndicka; Wesley, Koné, Pellegrini, Tsimikas; Dybala, Soulé, Dovbyk.
Roma player to watch vs Inter Milan
Having missed the previous four games due to a hamstring injury, Paulo Dybala came off the bench in Florence, so could start for just the second time under Gasperini. The Argentine attacker has previously netted five times against Inter, so can he add to that tally at the Olimpico?
Inter Milan team news
Cristian Chivu will make this a battle of the back threes, having very much maintained the shape and style that worked so well under his predecessor Simone Inzaghi.
With Marcus Thuram still sidelined due to a thigh injury, Ange-Yoan Bonny started and scored against Cremonese, hoping to keep his place over Francesco Pio Esposito.
Manuel Akanji meantime has started all four Serie A matches since arriving from Manchester City, while Chivu has a decision to make in midfield. Davide Frattesi completed the trio last time out, alongside Nicolò Barella and Henrikh Mkhitaryan, but any of Hakan Çalhanoğlu, Petar Sučić or Piotr Zieliński could well come into the team this time.
Inter Milan predicted lineup vs Roma: (3-5-3): Sommer; de Vrij, Akanju, Bastoni; Dumfries, Mkhitaryan, Çalhanoğlu, Barella, Dimarco; Bonny, Martínez.
Inter Milan player to watch vs Roma
Lautaro Martínez has, bizarrely, only ever scored twice in 14 meetings with Roma, albeit one of which was the only goal at Stadio Olimpico last season, so could he be Inter's capital city hero once again?
Roma vs Inter Milan prediction
This Saturday night clash is so tough to call, hence why we're forecasting a draw. This game though is more likely to be clichéd fascinating tactical battle, rather than a goal-fest: Roma 1-1 Inter Milan.
Roma vs Inter Milan FAQs - Serie A
How to watch Roma vs Inter Milan in Serie A on TV channel?
Roma vs Inter Milan in Serie A will be available on the following TV channels;
- UK: TNT Sports 1 & DAZN UK.
- USA: Paramount+
- Canada: Fubo Sports Network 2 Canada
How to watch Roma vs Inter Milan in Serie A on live streaming?
Roma vs Inter Milan in Serie A will be available on the following streaming services;
- UK: Discovery+ & DAZN UK.
- USA: Paramount+
- Canada: fuboTV Canada
What is the date and kick-off time for Roma vs Inter Milan in Serie A?
Roma vs Inter Milan takes place on Saturday 18 October 2025, with kick off at 19:45 (BST), 14:45 (EDT) & 11:45 (PDT).