Borussia Dortmund won 4-2 at the BayArena back in May, unbeaten in four trips to Leverkusen, winning three of them.
The last 17 meetings between these two clubs have produced 75 goals, meaning one is scored every 20 minutes on average.
Bayer Leverkusen vs Borussia Dortmund preview
With Bayern Munich cruising to yet another Meisterschale, these two are the only clubs since 2009 to deny die Rekordmeister the Bundesliga title, but are merely jostling to be the best of the rest right now. Of the pair, Bayer Leverkusen kick off one point better off, having really found form since Erik ten Hag's ill-fated two match tenure. On Tuesday night, die Werkself claimed a memorable Champions League victory, beating Manchester City 2-0 at the Etihad, thanks to goals from Álex Grimaldo and then Patrik Schick, securing a sizeable shock.

Meantime, in the Bundesliga, Kasper Hjulmand's team have won six of their last seven, beaten only by Bayern Munich since the opening day under ten Hag. A week ago, die Schwarzroten swatted aside an admittedly hapless Wolfsburg, 3-0 up inside 33 minutes, with Jonas Hofmann, Edmond Tapsoba and Malik Tillman all on target at the Volkswagen Arena. This has seen Bayer climb up to third, two points below RB Leipzig, looking to further cement their top four position with a victory here.
Borussia Dortmund meantime are only a point below their hosts, having also enjoyed a Champions League victory on Tuesday. Die Schwarzgelben smashed Villarreal 4-0 at the Westfalenstadion, with Serhou Guirassy scoring twice, Karim Adeyemi and Daniel Svensson also netting while Fábio Silva also missed a late spot-kick. The 2024 finalists have now collected a respectable ten points from their five league phase fixtures, with Bodø/Glimt, Tottenham and Inter their remaining opponents.

However, in the Bundesliga, Dortmund continue to be, well, Dortmund. Last Saturday, despite being 2-0 up and cruising at half time, Niko Kovač's team found themselves drawing 2-2 with Stuttgart, only for Adeyemi to restore their advantage a minute from time, but die Schwaben still had time to equalise right at the death. Having also conceded a stoppage time equaliser before the international break, die Schwarzgelben have won just two of their last six, unable to keep pace with leaders Bayern.
This is the first of two meetings between Dortmund and Leverkusen in the space of four days, clashing at Westfalenstadion in the DFB-Pokal on Tuesday. Around 43 miles south at the BayArena, who will win this Bundesliga meeting on Saturday evening?
Bayer Leverkusen vs Borussia Dortmund head-to-head record
- Matches Played: 108.
- Bayer Leverkusen Wins: 34. Draws: 27. Borussia Dortmund Wins: 47.
Bayer Leverkusen team news
Captain Robert Andrich and Edmond Tapsoba can both return at centre-back, having served their UEFA suspensions at the Etihad, likely to come in for Jeanuël Belocian as well as Jarell Quansah.

Further forward, Jonas Hofmann is not in the European squad but did score at Wolfsburg last weekend so may return; Lucas Vázquez, Equi Fernández and Exequiel Palacios are all injured.
Bayer Leverkusen predicted lineup vs Borussia Dortmund: (3-4-2-1): Flekken; Badé, Tapsoba, Andrich; Hofmann, Maza, García, Poku, Tillman, Grimaldo, Schick.
Bayer Leverkusen player to watch vs Borussia Dortmund
USMNT international Malik Tillman scored his third Bundesliga goal of the season last weekend, previously on target against Werder Bremen and Borussia Mönchengladbach, so can he add to his tally?
Borussia Dortmund team news
Niko Kovač is delighted that the experienced Emre Can is back, appearing in each of the last four matches having been sidelined due to an adductor injury, not featuring at all this season beforehand.

Elsewhere, Marcel Sabitzer could continue to get the nod over Pascal Groß, Jobe Bellingham and Carney Chukwuemeka at the base of midfield, albeit the latter duo did both start last weekend.
Borussia Dortmund predicted lineup vs Bayer Leverkusen: (3-4-2-1): Kobel; Anselmino, Anton, Schlotterbeck; Couto, Nmecha, Groß, Svensson; Brandt, Adeyemi, Guirassy.
Borussia Dortmund player to watch vs Bayer Leverkusen
Serhou Guirassy continues to be one of the most underrated strikers in Europe, taking his tally to nine for the season against Villarreal, having bagged 38 across all competitions last year. The Guinean netted home and away against Bayer last season, so will he repeat the trick here?
Bayer Leverkusen vs Borussia Dortmund prediction
If you're planning to tune into this one, do so expecting goals, with entertainment guaranteed, but we can't seperate the pair, so we're going for a score draw: Bayer Leverkusen 2-2 Borussia Dortmund.
Bayer Leverkusen vs Borussia Dortmund FAQs - Bundesliga
How to watch Bayer Leverkusen vs Borussia Dortmund in the Bundesliga on TV channel?
Bayer Leverkusen vs Borussia Dortmund in the Bundesliga will be available on the following TV channels;
- UK: Sky Sports Football
- USA: ESPN Select
- Canada: DAZN Canada
How to watch Bayer Leverkusen vs Borussia Dortmund in the Bundesliga on live streaming?
Bayer Leverkusen vs Borussia Dortmund in the Bundesliga will be available on the following streaming services;
- UK: SkyGo & NOW TV.
- USA: ESPN Select
- Canada: DAZN Canada
What is the date and kick-off time for Bayer Leverkusen vs Borussia Dortmund in the Bundesliga?
Bayer Leverkusen vs Borussia Dortmund takes place on Saturday 29 November 2025, with kick off at 17:30 (GMT), 12:30 (ET) & 9:30 (PT).
